کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2049161 1074118 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Structure of a polyisoprenoid binding domain from Saccharophagus degradans implicated in plant cell wall breakdown
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Structure of a polyisoprenoid binding domain from Saccharophagus degradans implicated in plant cell wall breakdown
چکیده انگلیسی

Saccharophagus degradans belongs to a recently discovered group of marine bacteria equipped with an arsenal of sugar cleaving enzymes coupled to carbohydrate-binding domains to degrade various insoluble complex polysaccharides. The modular Sde-1182 protein consists of a family 2 carbohydrate binding module linked to a X158 domain of unknown function. The 1.9 Å and 1.55 Å resolution crystal structures of the isolated X158 domain bound to the two related polyisoprenoid molecules, ubiquinone and octaprenyl pyrophosphate, unveil a β-barrel architecture reminiscent of the YceI-like superfamily that resembles the architecture of the lipocalin fold. This unprecedented association coupling oxidoreduction and carbohydrate recognition events may have implications for effective nutrient uptake in the marine environment.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 584, Issue 8, 16 April 2010, Pages 1577–1584
نویسندگان
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