کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2049174 1074119 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Biochemical characterization of an ABC transporter LptBFGC complex required for the outer membrane sorting of lipopolysaccharides
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Biochemical characterization of an ABC transporter LptBFGC complex required for the outer membrane sorting of lipopolysaccharides
چکیده انگلیسی

Seven Lpt proteins (A through G) are thought to be involved in lipopolysaccharide transport from the inner to outer membrane of Escherichia coli. LptB belongs to the ATP-binding cassette transporter superfamily. Although the lptB gene lacks neighboring genes encoding membrane subunits, bioinformatic analyses recently indicated that two distantly located consecutive genes, lptF and lptG, could encode membrane subunits. To examine this possibility, LptB was expressed with LptF and LptG. We report here that both LptF and LptG formed a complex with LptB. Furthermore, an inner membrane protein, LptC, which had been implicated in lipopolysaccharide transport, was also included in this complex.Structured summaryMINT-7137021: lptb (uniprotkb:P0A9V1) physically interacts (MI:0914) with lptc (uniprotkb:P0ADV9), lptg (uniprotkb:P0ADC6) and lptf (uniprotkb:P0AF98) by pull down (MI:0096)MINT-7137160: lptb (uniprotkb:P0A9V1) physically interacts (MI:0914) with lptf (uniprotkb:P0AF98) and lptg (uniprotkb:P0ADC6) by pull down (MI:0096)

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 583, Issue 13, 7 July 2009, Pages 2160–2164
نویسندگان
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