کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2049225 | 1074120 | 2010 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Candida albicansPHO81 is required for the inhibition of hyphal development by farnesoic acid
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Candida albicansPHO81 is required for the inhibition of hyphal development by farnesoic acid Candida albicansPHO81 is required for the inhibition of hyphal development by farnesoic acid](/preview/png/2049225.png)
چکیده انگلیسی
Farnesoic acid is a signaling molecule that inhibits the transition from budding yeast to filament formation in Candida albicans, but the molecular mechanism regulated by this substance is unknown. In this study, we analyzed the function of CaPHO81, which is induced by farnesoic acid. The pho81Δ mutant cells existed exclusively as filaments under favorable yeast growth conditions. Furthermore, the inhibition of hyphal growth and repression of CPH1, EFG1, HWP1, and GAP1 mRNA expression in response to farnesoic acid were defective in pho81Δ mutant cells. These data suggest a role for CaPHO81 in the inhibition of hyphal development by farnesoic acid.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 584, Issue 22, 19 November 2010, Pages 4639–4645
Journal: FEBS Letters - Volume 584, Issue 22, 19 November 2010, Pages 4639–4645
نویسندگان
Soon-Chun Chung, Tae-Im Kim, Chan-Hong Ahn, Jongheon Shin, Ki-Bong Oh,