کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2049249 1074121 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Cvt pathway as a model for selective autophagy
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
The Cvt pathway as a model for selective autophagy
چکیده انگلیسی

Autophagy is a highly conserved, ubiquitous process that is responsible for the degradation of cytosolic components in response to starvation. Autophagy is generally considered to be non-selective; however, there are selective types of autophagy that use receptor and adaptor proteins to specifically isolate a cargo. One type of selective autophagy in yeast is the cytoplasm to vacuole targeting (Cvt) pathway. The Cvt pathway is responsible for the delivery of the hydrolase aminopeptidase I to the vacuole; as such, it is the only known biosynthetic pathway that utilizes the core machinery of autophagy. Nonetheless, it serves as a model for the study of selective autophagy in other organisms.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 584, Issue 7, 2 April 2010, Pages 1359–1366
نویسندگان
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