کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2049777 1074142 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Robustness and topology of the yeast cell cycle Boolean network
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Robustness and topology of the yeast cell cycle Boolean network
چکیده انگلیسی

Yeast cell cycle Boolean network was used as a case study of robustness to protein noise. Robustness was interpreted as involving stability of G1 steady state and sequence of gene expression from cell cycle START to stationary G1. A robustness measure to evaluate robustness strength of a network was proposed. Robust putative networks corresponding to the same steady state and sequence of gene expression of wild-type network were sampled. Architecture of wild-type yeast cell cycle network can be revealed by average topology profile of sampled robust putative networks.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 583, Issue 5, 4 March 2009, Pages 927–932
نویسندگان
, ,