کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2050380 1074168 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Putative role for ABC multidrug exporters in yeast quorum sensing
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Putative role for ABC multidrug exporters in yeast quorum sensing
چکیده انگلیسی

Pleiotropic drug resistance (PDR) transporters play essential roles in cell resistance to various toxic compounds in various organisms including bacteria, mammals and yeasts. A large group of PDR transporters have been described in yeasts so far, including those that are controlled by transcription factor Pdr1p. Here, we show that besides their role in removing extracellularly added toxic compounds, the Pdr5p and Snq2p transporters play important physiological roles and significantly influence the developmental phases and physiology of yeast populations growing in a liquid culture. They appear to be involved in population quorum sensing, which consequently influences transcription factor Pdr1p level via feedback regulation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 583, Issue 7, 2 April 2009, Pages 1107–1113
نویسندگان
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