کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2051780 | 1074210 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Stg1 is a novel SM22/transgelin-like actin-modulating protein in fission yeast
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
We identified a novel actin-modulating protein Stg1 in the fission yeast Schizosaccharomyces pombe. Stg1 is similar to mammalian SM22/transgelin, and biochemical experiments showed that Stg1 crosslinked F-actin. Microscopic observation suggested that Stg1 was a component of actin patch. Overexpression of Stg1 caused a defect in cytokinesis by suppressing the formation of a contractile ring and formation of abnormal aggregates of F-actin in the ends and mid-region of cells. Although distribution of the actin cytoskeleton was not affected by disrupting stg1+, genetic interaction suggested that Stg1 was likely involved in controlling the organization of the actin cytoskeleton in cell morphogenesis and cytokinesis in fission yeast.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 579, Issue 28, 21 November 2005, Pages 6311–6316
Journal: FEBS Letters - Volume 579, Issue 28, 21 November 2005, Pages 6311–6316
نویسندگان
Kentaro Nakano, Fumihide Bunai, Osamu Numata,