کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2052637 1074235 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Changes in subcellular localization of fructose 1,6-bisphosphatase during differentiation of isolated muscle satellite cells
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Changes in subcellular localization of fructose 1,6-bisphosphatase during differentiation of isolated muscle satellite cells
چکیده انگلیسی

Subcellular localization of FBPase, a regulatory enzyme of glyconeogenesis, was examined inside dividing and differentiating satellite cells from rat muscle. In dividing myoblasts, FBPase was located in cytosol and nuclei. When divisions ceased, FBPase became restricted to the cytosolic compartment and finally was found to associate with the Z-lines, as in adult muscle. Moreover, a 12-fold decrease was observed in the number of FBPase-positive nuclei associated with muscle fibres of adult rat, as compared with young muscle, possibly reflecting the reduction in number of active satellite cells during muscle maturation. The data might suggest that FBPase participates in some nuclear processes during development and regeneration of skeletal muscle.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 580, Issue 17, 24 July 2006, Pages 4042–4046
نویسندگان
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