کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2052941 | 1074245 | 2006 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Molecular nature of methicillin-resistant Staphylococcus aureus derived from explosive nosocomial outbreaks of the 1980s in Japan
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش گیاه شناسی
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) with Panton-Valentine leukocidin (PVL) genes is increasing worldwide. Nosocomial outbreak-derived (hospital-acquired) MRSA (HA-MRSA) in Japan in the 1980s was also largely PVL+. PVL+ HA-MRSA and CA-MRSA shared the same multi-locus sequence type (ST30) and methicillin resistance cassette (SCCmecIV), but were divergent in oxacillin resistance, spa typing, PFGE analysis or clfA gene analysis. PVL+ HA-MRSA, which probably originated in PVL+S. aureus ST30, was highly adhesive (carrying cna and bbp genes), highly-toxic (carrying lukPV and sea genes) and highly drug-resistant. PVL+ HA-MRSA was once replaced by other PVL− HA-MRSA (e.g., ST5), and is re-emerging as CA-MRSA.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 580, Issue 9, 17 April 2006, Pages 2323–2334
Journal: FEBS Letters - Volume 580, Issue 9, 17 April 2006, Pages 2323–2334
نویسندگان
Ikue Taneike, Taketo Otsuka, Soshi Dohmae, Kohei Saito, Kyoko Ozaki, Misao Takano, Wataru Higuchi, Tomomi Takano, Tatsuo Yamamoto,