Recent highlights in anti-protozoan drug development and resistance research

This article summarizes the highlights of research presented in January, 2012, at the Keystone Symposium on “Drug Discovery for Protozoan Parasites” held in Santa Fe, New Mexico. This symposium which convenes approximately every 2 years provides a forum for leading investigators around the world to present data covering basic sciences to clinical trials relating to anti-protozoan drug development and drug resistance. Many talks focused on malaria, but other protozoan diseases receiving attention included African sleeping sickness, Chagas disease, leishmaniasis, cryptosporidiosis, and amoebiasis. The new research, most of it unpublished, provided insights into the latest developments in the field.

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• The Keystone Symposium on Drug Discovery for Protozoan Parasites took place in January, 2012, in Santa Fe, NM.
• Highlights in the progress in antimalarial drug discovery and malaria drug resistance research are presented in this review.
• Highlights of recent advances in drug development against trypanosomes, Leishmania, amoebas, and other pathogens are also presented.