کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2062791 1544061 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The culture of human cleavage stage embryos alone or in groups: effect upon blastocyst utilization rates and implantation
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
The culture of human cleavage stage embryos alone or in groups: effect upon blastocyst utilization rates and implantation
چکیده انگلیسی

SUMMARYThe effect of cleavage–stage group culture (CGC; embryos cultured in groups of three or more for the first 3 days and then individually to blastocyst) was compared to extended single embryo culture (ESC; embryos cultured individually to the blastocyst stage). While implantation and ongoing pregnancy rates were similar between groups, the blastocyst utilization rate (number of blastocysts suitable for freezing and thawing/total number of embryos cultured to Day 5 and 6) was significantly higher when embryos were cultured in CGC for women <35 yrs thereby increasing the number of embryos available for clinical use for the younger women. This strategy of group culture to Day 3 would seem an ideal protocol to capitalize on an overall embryo quality in two particular settings, namely programmes wishing to (i) undertake Day 3 transfers, and (ii) keep embryos separate from Day 3 to Day5/6 for the purposes of selection. The culture system can also be applied to the embryos of older women without adverse effect, enabling the same system to be used for all embryos.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive Biology - Volume 10, Issue 3, November 2010, Pages 227–234
نویسندگان
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