کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2068994 1078370 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Seven large variations in the extent of RNA editing in plant mitochondria between three ecotypes of Arabidopsis thaliana
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوفیزیک
پیش نمایش صفحه اول مقاله
Seven large variations in the extent of RNA editing in plant mitochondria between three ecotypes of Arabidopsis thaliana
چکیده انگلیسی

Most RNA editing sites in flowering plant mitochondria are located in coding regions of mRNAs and are usually essential for correct gene expression. Although accordingly little variation should be tolerated, editing sites appear and disappear even between closely related flowering plant species. To investigate whether such editing site variations also occur within species, we analyzed 379 RNA editing sites in the three ecotypes Columbia, Landsberg erecta and C24 of Arabidopsis thaliana. While all editing sites as such are conserved, we identify seven RNA editing sites with 40–60% differences in effective editing between individual ecotypes. These quantitative variations show that the extent of RNA editing in plant mitochondria is very flexible and can change even more rapidly than the evolution of species. The ecotype-specific variations of the RNA editing extent are Mendelian-inherited and can now be used to follow and identify the nuclear loci responsible for these RNA editing phenotypes.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mitochondrion - Volume 8, Issue 4, September 2008, Pages 319–327
نویسندگان
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