کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2069637 1078414 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The uptake and distribution of coenzyme Q(10)
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوفیزیک
پیش نمایش صفحه اول مقاله
The uptake and distribution of coenzyme Q(10)
چکیده انگلیسی

This review describes recent advances in our understanding of the uptake and distribution of coenzyme Q10 (CoQ10) in cells, animals, and humans. These advances have provided evidence of important pharmacokinetic factors, such as non-linear absorption and enterohepatic recirculation, and may facilitate the development of new CoQ10 formulations. Studies providing data which support the claim of tissue uptake of exogenous CoQ10 are also discussed. Improved CoQ10 dosing and drug level monitoring guidelines are suggested for adult and pediatric patient populations. Future CoQ10 research should consider uptake and distribution factors to determine cost-benefit relationships.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mitochondrion - Volume 7, Supplement, June 2007, Pages S72–S77
نویسندگان
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