کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2074503 1544811 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Differential expression of lipopolysaccharide-induced TNF-α factor (LITAF) in reproductive tissues during induced molting of white leghorn hens
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Differential expression of lipopolysaccharide-induced TNF-α factor (LITAF) in reproductive tissues during induced molting of white leghorn hens
چکیده انگلیسی

The reproductive remodeling during molting appears to be a complex physiological mechanism regulated by multiple host factors. Lipopolysaccharide (LPS) induced TNF-α factor (LITAF) is one of the transcription factors controlling the expression of TNF-α and other cytokines. In the present investigation, we studied the involvement of LITAF in the regression of reproductive tissues of molting birds. Semi-quantitative RT-PCR analysis revealed that LITAF mRNA was generally expressed in both ovary and oviduct. In the molting birds, i.e. those subjected to feed withdrawal (FW) or fed high levels of zinc (ZnF) birds, the LITAF expression was upregulated significantly in the ovary after 4 days of molting (DOM). However, LITAF mRNA levels were three-fold higher in ZnF birds, which might be responsible for a greater degree of follicular atresia. In the oviduct of FW birds, peak LITAF expression was noticed on 4DOM and the levels remained significantly higher until the end of the experiment. In ZnF birds, LITAF expression reached its peak on 1DOM and subsequently downregulated to basal levels on 2DOM. This indicated that constantly higher LITAF expression might be required for complete regression of the oviduct during molting. In conclusion, LITAF might be one of the major transcription factors controlling reproductive regression in chicken, as the expression levels were associated with the regression pattern.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Animal Reproduction Science - Volume 102, Issues 3–4, December 2007, Pages 335–342
نویسندگان
, , , , , ,