کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2100287 1082992 2013 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Treatment strategies for peripheral T-cell lymphomas
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Treatment strategies for peripheral T-cell lymphomas
چکیده انگلیسی

Peripheral T-cell lymphomas (PTCL) are a heterogeneous group of clinically aggressive diseases historically associated with inferior outcomes using conventional lymphoma therapies. Aggressive first line therapy and consolidation with autologous stem cell transplantation has led to improved survival, but the majority of patients either fails to respond to therapy or are not transplant candidates. Novel approaches have included new classes of drug and biological agents, including antifolates, immunoconjugates, histone deacetylase (HDAC) inhibitors, monoclonal antibodies, and signal transduction inhibitors. Molecular profiling has led to identification of relevant pathways for future novel approaches.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Haematology - Volume 26, Issue 1, March 2013, Pages 43–56
نویسندگان
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