کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2100509 1083004 2007 20 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chemoimmunotherapy of chronic lymphocytic leukemia
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Chemoimmunotherapy of chronic lymphocytic leukemia
چکیده انگلیسی
The past two decades have seen a major paradigm shift in the therapy of chronic lymphocytic leukemia (CLL), with the treatment goal shifting from symptom palliation to the attainment of maximal disease control using the most effective frontline regimens available, thus prolonging survival and possibly leading to cure. The most potent therapeutic regimens developed to date include the chemoimmunotherapy combinations incorporating purine analogs and monoclonal antibodies. We review the evolution of modern chemoimmunotherapy for CLL, and discuss current research directions for further refining the potency of these regimens.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Haematology - Volume 20, Issue 3, September 2007, Pages 479-498
نویسندگان
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