کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2100750 1083065 2009 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Standardisation of molecular monitoring for chronic myeloid leukaemia
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Standardisation of molecular monitoring for chronic myeloid leukaemia
چکیده انگلیسی

Molecular monitoring of chronic myeloid leukaemia (CML) patients by real time quantitative reverse transcriptase PCR (RQ-PCR) is of clinical value, but the use of diverse laboratory protocols and units of measurement make it difficult to compare results between and sometimes within centres. This review explores the intrinsic difficulties in standardising the RQ-PCR analysis, summarises the progress that has been made following the proposal for a new International Scale for BCR-ABL measurement and discusses how further improvements are likely to be made.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Haematology - Volume 22, Issue 3, September 2009, Pages 355–365
نویسندگان
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