کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2100967 1083092 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Adipose tissue cells, lipotransfer and cancer: A challenge for scientists, oncologists and surgeons
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Adipose tissue cells, lipotransfer and cancer: A challenge for scientists, oncologists and surgeons
چکیده انگلیسی

Despite recent evidence of the cancer-promoting role of adipose tissue-derived progenitor and differentiated cells, the use of lipotransfer for tissue/organ reconstruction after surgical removal of cancer is increasing worldwide. Here we discuss in a multidisciplinary fashion the preclinical data connecting obesity, adipose cells and cancer progression, as well as the clinical data concerning safety of lipotransfer procedures in cancer patients. A roadmap towards a more rationale use of lipotransfer in oncology is urgently needed and should include preclinical studies to dissect the roles of different adipose tissue-derived cells, the evaluation of drugs currently candidate to inhibit the interaction between adipose and tumor cells, and carefully designed clinical trials to investigate the safety of lipotransfer procedures in cancer patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochimica et Biophysica Acta (BBA) - Reviews on Cancer - Volume 1826, Issue 1, August 2012, Pages 209–214
نویسندگان
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