کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2106371 1083512 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessment and management of high-risk pregnancies in women with thrombophilia
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Assessment and management of high-risk pregnancies in women with thrombophilia
چکیده انگلیسی

SummaryPregnancy is an acquired hypercoagulable state which can lead to gestational vascular complications especially in the presence of other prothrombotic risk factors. The use of anticoagulation for prevention of pregnancy complications in women with thrombophilia is becoming more frequent. Efficacy and safety issues of therapeutic and prophylactic regimens use and monitoring of LMWH therapy in pregnancy are discussed in this review. In addition, a scoring system for women with thrombophilia is proposed which includes severity of pregnancy outcomes, thrombotic history and type of thrombophilia.Validation of this scoring system has revealed a significant correlation between the proposed score and LMWH dosages that were prescribed to the studied pregnant women.Careful diagnosis, observation and monitoring can add significant benefit to LMWH therapy during pregnancy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Blood Reviews - Volume 23, Issue 4, July 2009, Pages 143–147
نویسندگان
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