کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2106630 1083558 2010 22 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Pathophysiology and management of inherited bone marrow failure syndromes
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Pathophysiology and management of inherited bone marrow failure syndromes
چکیده انگلیسی

The inherited marrow failure syndromes are a diverse set of genetic disorders characterized by hematopoietic aplasia and cancer predisposition. The clinical phenotypes are highly variable and much broader than previously recognized. The medical management of the inherited marrow failure syndromes differs from that of acquired aplastic anemia or malignancies arising in the general population. Diagnostic workup, molecular pathogenesis, and clinical treatment are reviewed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Blood Reviews - Volume 24, Issue 3, May 2010, Pages 101–122
نویسندگان
, ,