کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2114425 1084537 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cinnamon extract suppresses tumor progression by modulating angiogenesis and the effector function of CD8+ T cells
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Cinnamon extract suppresses tumor progression by modulating angiogenesis and the effector function of CD8+ T cells
چکیده انگلیسی

Cinnamon is one of the most widely used herbal medicines with diverse bioactive effects. However, little evidence has been reported about the potential anti-tumor effects of cinnamon. In vitro and in vivo system, cinnamon treatment strongly inhibited the expression of pro-angiogenic factors and master regulators of tumor progression not only in melanoma cell lines but also in experimental melanoma model. In addition, cinnamon treatment increased the anti-tumor activities of CD8+ T cells by increasing the levels of cytolytic molecules and their cytotoxic activity. In conclusion, cinnamon extract has the potential to be an alternative medicine for tumor treatment.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer Letters - Volume 278, Issue 2, 18 June 2009, Pages 174–182
نویسندگان
, , , , , , , ,