Comparison of murine gene expression profiles between spontaneous and radiation-induced myelogenous leukemias: Stochastic and probabilistic expression variances in the former vs radiation-specific expression commonalities in the latter

Discriminant union genes in radiation-induced myelogenous leukemias against spontaneous myelogenous leukemias and age-matched nonleukemic bone marrow profilings generated by unsupervised computational analysis essentially represent probabilistic biomarkers for radiation-induced myelogenous leukemias, which may contribute to developing a model for risk of secondary carcinogenesis in patients treated by whole-body irradiation.