Stimulation of osteoclastogenesis by enhanced levels of MIP-1α in BALB/c mice in vitro

MIP-1α, induced by RANKL during OC differentiation, increases OC formation by acting on OC progenitor cells, and prolongs survival of mature OC via signaling through NF-κB. The enhanced OC formation in BMM from B/c mice could be due to, at least in part, to their higher levels of MIP-1α.