کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2135617 1087627 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Natural killer cells: In health and disease
ترجمه فارسی عنوان
سلول های قاتل طبیعی: در سلامتی و بیماری
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی

Natural killer (NK) cells constitute our bodies’ frontline defense system, guarding against tumors and launching attacks against infections. The activities of NK cells are regulated by the interaction of various receptors expressed on their surfaces with cell surface ligands. While the role of NK cells in controlling tumor activity is relatively clear, the fact that they are also linked to various other disease conditions is now being highlighted. Here, we present an overview of the role of NK cells during normal body state as well as under diseased state. We discuss the possible utilization of these powerful cells as immunotherapeutic agents in combating diseases such as asthma, autoimmune diseases, and HIV-AIDS. This review also outlines current challenges in NK cell therapy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hematology/Oncology and Stem Cell Therapy - Volume 8, Issue 2, June 2015, Pages 47–55
نویسندگان
, ,