کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2135620 | 1087627 | 2015 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Plasma cell leukemia: Clinicopathologic, immunophenotypic and cytogenetic characteristics of 4 cases Plasma cell leukemia: Clinicopathologic, immunophenotypic and cytogenetic characteristics of 4 cases](/preview/png/2135620.png)
Plasma cell leukemia (PCL) is a rare hematologic malignancy with very poor outcome. It is defined by the presence of >2 × 109/L plasma cells or >20% plasmacytosis of the differential white cell count in the peripheral blood. Primary PCL is first diagnosed in the leukemic phase, while secondary PCL corresponds to the leukemic transformation of a previously diagnosed multiple myeloma (MM). The incidence of PCL ranges between 2–4% of patients with MM and 0.9% of patients with acute leukemia. In this case series, we describe the clinicopathologic, immunophenotypic, and cytogenetic findings of four patients diagnosed with PCL within a ten-year period (2002–2012) at King Faisal Specialist Hospital and Research Centre (General Organization), Riyadh, Saudi Arabia.
Journal: Hematology/Oncology and Stem Cell Therapy - Volume 8, Issue 2, June 2015, Pages 71–77