Mechanism of paroxysmal nocturnal hemoglobinuria clonal dominance: possible roles of different apoptosis and CD8 + lymphocytes in the selection of paroxysmal nocturnal hemoglobinuria clones

Increased apoptosis of GPI + blood cells is likely to be responsible in selection and expansion of PNH clones. MNCs or possibly CD8 + lymphocytes may play a role in this phenomenon.