کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2136962 | 1087827 | 2013 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Lack of association between TNF-α promoter polymorphisms and multiple myeloma: A meta-analysis
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Results of available literatures, which concerned the association between TNF-α promoter −238/−308 gene polymorphisms and multiple myeloma (MM), are of great controversy. A review was performed in studies reporting on the association between them. Odds ratios (ORs) with 95% confidence interval (CI) were used to evaluate the association. The pooled ORs indicated that there was no association between TNF-α −238/−308 polymorphisms and MM susceptibility in overall population. Sub-group analysis also confirmed that no evidence supported the relevance of TNF-α promoter −238/−308 gene polymorphisms with MM. Studies with large sample size and multi-ethnics may be needed to further explore the association between them.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Leukemia Research - Volume 37, Issue 1, January 2013, Pages 50–57
Journal: Leukemia Research - Volume 37, Issue 1, January 2013, Pages 50–57
نویسندگان
Bing Li, Xiao-Dan Wang, Xiaolei Sun, Jianxiong Ma, Yang Yang, Xinlong Ma,