کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2146008 | 1088844 | 2008 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Circulating tumour cells as a predictive factor for response to systemic chemotherapy in patients with advanced colorectal cancer
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Circulating tumour cells as a predictive factor for response to systemic chemotherapy in patients with advanced colorectal cancer Circulating tumour cells as a predictive factor for response to systemic chemotherapy in patients with advanced colorectal cancer](/preview/png/2146008.png)
چکیده انگلیسی
Circulating tumour cells (CTC) can be traced in patients with different types of cancer. The aim of this study was to detect CTC in patients with advanced colorectal cancer and whether CTC are still detectable after systemic chemotherapy. Blood from 34 patients with advanced colorectal cancer was analysed for the presence of CTC before chemotherapy was given and after 3Â months. Eleven patients demonstrated a tumour remission after chemotherapy. In 6 cases CTC were detectable before but not after initiation of chemotherapy. Ten patients demonstrated a progression. In 5 cases CTC were detected before and after chemotherapy. Our data suggest that the detection of CTC will help to identify patients responding to chemotherapy or with a risk of a therapy failure.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Molecular Oncology - Volume 2, Issue 4, December 2008, Pages 349-355
Journal: Molecular Oncology - Volume 2, Issue 4, December 2008, Pages 349-355
نویسندگان
Silke Lankiewicz, Silke Zimmermann, Christiane Hollmann, Tina Hillemann, Tim F. Greten,