کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2147690 | 1548421 | 2006 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Cellular radiation effects and the bystander response Cellular radiation effects and the bystander response](/preview/png/2147690.png)
This report reviews briefly some of the findings reported over the past 2 years that enhance our understanding of the radiation-induced bystander effect. These developments include: technicological advances; the role of oxidative stress; the effect of cytoplasmic irradiation; cell-to-cell communication; and evidence that Connexin 43 mediated intercellular communication is induced by radiation exposure. A few overriding unanswered questions are discussed. These include: what is the signal(s) transmitted from irradiated to bystander cells; what is the relationship between the bystander response and other non-targeted effects of radiation; are there beneficial effects associated with the bystander response; and what is the significance of the bystander effect for radiation protection?
Journal: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis - Volume 597, Issues 1–2, 11 May 2006, Pages 113–118