Evaluation of the Litron In Vitro MicroFlow® Kit for the flow cytometric enumeration of micronuclei (MN) in mammalian cells

The inconsistencies observed between flow cytometry and standard microscopy, and the differences in assay sensitivity, particularly for apoptosis-inducing compounds, suggest that the prototype In Vitro MicroFlow® Kit requires further refinement. Studies to investigate new parameters to address these issues are now under way and will be reported separately.