کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2152881 1090143 2014 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Small volume of the posterior cranial fossa and arterial hypertension are risk factors of hemifacial spasm
ترجمه فارسی عنوان
حجم کم مجرای خلفی جمجمه و فشار خون شریانی عوامل خطرساز اسپاسم همی فاسیال
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی

ObjectivesSo far, there are only two studies evaluating the relation between the small volume of the posterior cranial fossa (VPCF) and the occurrence of HFS, both on Asian population. The aim of the study was to determine small VPCF and arterial hypertension (AH), as risk factors for hemifacial spasm (HFS) and their relation to neurovascular conflict (NVC) in Polish Caucasian-origin patients.Materials and methodsThe study included 60 patients with idiopathic HFS and 60 healthy volunteers matched by sex and age. AH was defined according to WHO. The VPCF measured the volume of the prepontine, prespinal and both cerebellopontine angle cisterns in MRI scans.ResultsThere were no significant differences between occurrence of AH and the VPCF of patients and controls but the mean VPCF in women was significantly smaller than in men, In the multivariate regression analysis model only NVC was the statistically significant. In the subgroup of >50-year-old patients the most dominant risk factor was NVC (OR 71.09; 95% CI 21.08–239.77; p = 0.0000), followed by the AH duration (OR 1.07; 95% CI 1.00–1.16; p = 0.047). In the subgroup of <50 years, NVC was also the dominant risk factor, followed by the lower VPCF (Walad test: OR 0.4; 95% CI 0.16–1.04; p = 0.045).ConclusionThere was no significant difference in VPCF and in frequency of AH diagnosis in HFS patients and age- and sex-related controls, but the logistic regression analysis showed that small VPCF and AH duration are risk factors of HFS in younger and older patients respectively.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurologia i Neurochirurgia Polska - Volume 48, Issue 6, November–December 2014, Pages 383–386
نویسندگان
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