کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2154575 | 1090241 | 2007 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Biodistribution of functionalized multiwall carbon nanotubes in mice
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
With the application of carbon nanotubes in biomedical and pharmaceutical sciences, its basic biological properties in vivo have become an issue of strong concern. Water-soluble functionalized multiwall carbon nanotubes (MWNTs) were labeled with radioactive 99mTc atoms, and then a tracer was used to study the distribution of MWNTs modified with glucosamine in mice. It shows that MWNTs moved easily among the compartments and tissues of the body, behaving like active molecules although their apparent mean molecular weight is tremendously large. In this study, water-soluble MWNTs were labeled with 99mTc for the first time, and all results on the distribution of MWNTs in animals provide useful data for their use in the biomedical field.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nuclear Medicine and Biology - Volume 34, Issue 5, July 2007, Pages 579–583
Journal: Nuclear Medicine and Biology - Volume 34, Issue 5, July 2007, Pages 579–583
نویسندگان
Jinxue Guo, Xiao Zhang, Qingnuan Li, Wenxin Li,