Influence of sedation and data acquisition method on tracer uptake in animal models: [123I]-2-iodo-l-phenylalanine in pentobarbital-sedated tumor-bearing athymic mice

An effect of sedation treatment and data acquisition method was demonstrated for 2-iodo-phenylalanine, currently under development as tumor tracer. It is recommended that animal experiments should include quantitative investigation of sedation and the data acquisition method.