کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2159195 | 1090852 | 2010 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Stereotactic radiotherapy for peripheral lung tumors: A comparison of volumetric modulated arc therapy with 3 other delivery techniques Stereotactic radiotherapy for peripheral lung tumors: A comparison of volumetric modulated arc therapy with 3 other delivery techniques](/preview/png/2159195.png)
PurposeVolumetric modulated arc therapy (RapidArc) allows for fast delivery of stereotactic body radiotherapy (SBRT) delivery in stage I lung tumors. We compared dose distributions and delivery times between RapidArc and common delivery techniques in small tumors.MethodsIn 18 patients who completed RapidArc SBRT for tumors measuring <70 cm3, new treatment plans were generated using non-coplanar 3D conformal fields (conf-SBRT) and dynamic conformal arc radiotherapy (DCA). For 9 patients with tumors adjacent to the chest wall, co-planar intensity-modulated radiotherapy (IMRT) plans were also generated. PTV dose coverage, organs at risk (OAR) doses and treatment delivery times were assessed.ResultsRapidArc plans achieved a superior conformity index (CI) and lower V45Gy to chest wall (p < 0.05) compared to all other techniques. RapidArc led to a small increase in V5Gy to contralateral lung compared to conf-SBRT (4.4 ± 4% versus 1.2 ± 1.8%, p = 0.011). For other OAR, RapidArc and conf-SBRT plans were comparable, and both were superior to DCA plans. Delivery of a 7.5 Gy-fraction required 3.9 min (RapidArc), 11.6 min (conf-SBRT), and 12 min (IMRT).ConclusionsIn stage I lung tumors measuring <70 cm3, RapidArc plans achieved both the highest dose conformity and shortest delivery times.
Journal: Radiotherapy and Oncology - Volume 97, Issue 3, December 2010, Pages 437–442