کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2161007 1090900 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
On the cost-effectiveness of Carbon ion radiation therapy for skull base chordoma
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
On the cost-effectiveness of Carbon ion radiation therapy for skull base chordoma
چکیده انگلیسی

AimThe cost-effectiveness of Carbon ion radiotherapy (RT) for patients with skull base chordoma is analyzed.Materials and MethodsPrimary treatment costs and costs for recurrent tumors are estimated. The costs for treatment of recurrent tumors were estimated using a sample of 10 patients presenting with recurrent chordoma at the base of skull at DKFZ. Using various scenarios for the local control rate and reimbursements of Carbon ion therapy the cost-effectiveness of ion therapy for these tumors is analyzed.ResultsIf local control rate for skull base chordoma achieved with carbon ion therapy exceeds 70.3%, the overall treatment costs for carbon RT are lower than for conventional RTI. The cost-effectiveness ratio for carbon RT is 2539 Euro per 1% increase in survival, or 7692 Euro per additional life year.ConclusionCurrent results support the thesis that Carbon ion RT, although more expensive, is at least as cost-effective as advanced photon therapies for these patients. Ion RT, however, offers substantial benefits for the patients such as improved control rates and less severe side effects.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Radiotherapy and Oncology - Volume 83, Issue 2, May 2007, Pages 133–138
نویسندگان
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