کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2161668 | 1090929 | 2006 | 6 صفحه PDF | دانلود رایگان |
PurposeUnderdosage in the human larynx may be the true factor behind the decrease in local control rates.Patients and methodsTo evaluate underdosage with Monte Carlo a CT-based geometrical model of the patient's neck (mathematical neck) was created. Dose was calculated for a pair of 6 Me V parallel-opposed photon beams modulated with 15 degree steel wedges.ResultsAt least 5% of volume of 3.5 cm3 hypothetical tumor near the air wall of the larynx receives less than 86% of the maximum tumor dose. The same volume received less than 91% of the maximum tumor dose when the mathematical neck had no air cavities.ConclusionsWe conclude the significant underdosage at the air-tissue interface in the larynx occurs in traditional radiotherapy treatments, especially in the glottic part of the larynx.
Journal: Radiotherapy and Oncology - Volume 78, Issue 2, February 2006, Pages 159–164