Promising Targets and Drugs in Development for Colorectal Cancer

Colorectal cancer (CRC) is one of the most common cancers and causes of cancer death in the world despite incremental improvement in the treatment of this disease. Advancements in the molecular understanding of CRC have led to new areas of therapeutic research. In this endeavor, numerous compounds with specific molecular targets are being developed in preclinical and early clinical studies. Molecular pathways involved in CRC and potentially effective targeted agents in development will be reviewed.