کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2162540 | 1091257 | 2009 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Ovarian Stromal and Germ Cell Tumors
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Cancers arising from the stromal and germ cell layers of the ovary are rare, heterogeneous, difficult to study, and require specialized multidisciplinary management. We present a clinically relevant review of the literature of these malignancies, with particular emphasis on the more typical presentations. These tumors more commonly present in younger patients and have a high cure rate. They are associated with serum markers that are informative for diagnosis and surveillance. Surgery is often part of primary treatment, with staging and preservation of fertility being important priorities. Most patients with germ cell tumors require adjuvant chemotherapy with bleomycin, etoposide, and cisplatin (BEP), as well as careful surveillance. The rarity of these tumors makes basic scientific advances more challenging.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Oncology - Volume 36, Issue 2, April 2009, Pages 126-136
Journal: Seminars in Oncology - Volume 36, Issue 2, April 2009, Pages 126-136
نویسندگان
Carolyn R. Koulouris, Richard T. Penson,