کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2164137 1091480 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cancer Genomics in Clinical Context
ترجمه فارسی عنوان
ژنومیک سرطان در زمینه بالینی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی
Precision medicine requires appropriate application of genomics in clinical practice. In cancer, we have witnessed practice-changing examples of how genomic knowledge is translated into more tailored and effective therapies. The next opportunity is to embed cancer genomics in clinical context so that patient-centric longitudinal clinical, genomic, and molecular phenotypes can be compiled for adaptive learning between precision medicine research and clinical care with the goal of accelerating clinically-actionable discoveries. We describe here an adaptive learning platform, APOLLO™ (adaptive patient-oriented longitudinal learning and optimization) designed to integrate genomic research in the context of, but not in the path of, routine and investigational clinical care for purposes of enabling data-driven discovery across disciplines such that every patient can contribute to and potentially benefit from research discoveries.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Trends in Cancer - Volume 1, Issue 1, September 2015, Pages 36-43
نویسندگان
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