کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2164137 | 1091480 | 2015 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cancer Genomics in Clinical Context
ترجمه فارسی عنوان
ژنومیک سرطان در زمینه بالینی
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
چکیده انگلیسی
Precision medicine requires appropriate application of genomics in clinical practice. In cancer, we have witnessed practice-changing examples of how genomic knowledge is translated into more tailored and effective therapies. The next opportunity is to embed cancer genomics in clinical context so that patient-centric longitudinal clinical, genomic, and molecular phenotypes can be compiled for adaptive learning between precision medicine research and clinical care with the goal of accelerating clinically-actionable discoveries. We describe here an adaptive learning platform, APOLLO⢠(adaptive patient-oriented longitudinal learning and optimization) designed to integrate genomic research in the context of, but not in the path of, routine and investigational clinical care for purposes of enabling data-driven discovery across disciplines such that every patient can contribute to and potentially benefit from research discoveries.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Trends in Cancer - Volume 1, Issue 1, September 2015, Pages 36-43
Journal: Trends in Cancer - Volume 1, Issue 1, September 2015, Pages 36-43
نویسندگان
Lynda Chin, Jennifer A. Wargo, Denise J. Spring, Hagop Kantarjian, P. Andrew Futreal,