کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2166202 | 1091827 | 2011 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Vacuolar Ca2+ uptake Vacuolar Ca2+ uptake](/preview/png/2166202.png)
Calcium transporters that mediate the removal of Ca2+ from the cytosol and into internal stores provide a critical role in regulating Ca2+ signals following stimulus induction and in preventing calcium toxicity. The vacuole is a major calcium store in many organisms, particularly plants and fungi. Two main pathways facilitate the accumulation of Ca2+ into vacuoles, Ca2+-ATPases and Ca2+/H+ exchangers. Here I review the biochemical and regulatory features of these transporters that have been characterised in yeast and plants. These Ca2+ transport mechanisms are compared with those being identified from other vacuolated organisms including algae and protozoa. Studies suggest that Ca2+ uptake into vacuoles and other related acidic Ca2+ stores occurs by conserved mechanisms which developed early in evolution.
Journal: Cell Calcium - Volume 50, Issue 2, August 2011, Pages 139–146