کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2170017 1093245 2010 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Molecules, mechanisms, and cellular roles of clathrin-independent endocytosis
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Molecules, mechanisms, and cellular roles of clathrin-independent endocytosis
چکیده انگلیسی

Eukaryotic cells deftly coordinate an array of endocytic pathways beyond the classical clathrin-mediated endocytic route. Although the existence of clathrin-independent endocytic pathways has been accepted for some time, only recently have tools been developed that specifically delineate their fine details, including molecular composition and ultrastructural morphology. Identification of the salient features of distinct pathways has concomitantly attributed them with specific roles during important cellular processes. Insight from model organisms confirms these roles and suggests maintenance of crucially adapted functions across species. Among other roles, clathrin-independent endocytosis has now been linked to plasma membrane repair, cellular spreading, cellular polarization, and modulation of intercellular signaling. The field is now primed to identify how these pathways function within physiologically relevant environments.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Cell Biology - Volume 22, Issue 4, August 2010, Pages 519–527
نویسندگان
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