کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2170821 1549506 2007 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nerve growth factor and tissue repair remodeling: trkANGFR and p75NTR, two receptors one fate
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Nerve growth factor and tissue repair remodeling: trkANGFR and p75NTR, two receptors one fate
چکیده انگلیسی

This review deals with the role of nerve growth factor (NGF) in healing process as a result of injury. The role of both trkANGFR and p75NTR specific NGF receptors and their contribution in the complex network of tissue repair process, is discussed and highlighted in view of recent findings. In fact, NGF represents a significant advance in the treatment of etiologically different ulcers (corneal ulcers, pressure ulcers, post-viral infections, chemical burns) and might shorten the recovery process. For these diseases, no specific treatment is actually available. It is reasonable that apart from NGF and/or neurotrophins a different time-course of trkANGRF/p75NTR expression, might regulate the final process.In summary, these novel findings on the potential pro-healing capacity of NGF might open new possibilities for this growth factor in modulating the healing processes in several pathological conditions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cytokine & Growth Factor Reviews - Volume 18, Issues 3–4, June–August 2007, Pages 245–256
نویسندگان
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