کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2173232 1093704 2013 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Enhancer activity sensitive to the orientation of the gene it regulates in the chordategenome
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Enhancer activity sensitive to the orientation of the gene it regulates in the chordategenome
چکیده انگلیسی
► Enhancers are flexible in terms of their location and orientation relative to the genes they regulate. ► Little is known about whether the flexibility can be applied in every combination of enhancers and genes. ► We identified enhancers sensitive to the orientation of the gene they regulate in the chordate genome. ► This suggests that the relative positions and orientations of genes and enhancers are not randomly determined. ► Such constraints may have determined the positions of enhancers and genes during the evolution of animal genomes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Developmental Biology - Volume 375, Issue 1, 1 March 2013, Pages 79-91
نویسندگان
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