کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2177123 1094624 2010 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Patterning a Complex Organ: Branching Morphogenesis and Nephron Segmentation in Kidney Development
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Patterning a Complex Organ: Branching Morphogenesis and Nephron Segmentation in Kidney Development
چکیده انگلیسی

The two major components of the kidney, the collecting system and the nephron, have different developmental histories. The collecting system arises by the reiterated branching of a simple epithelial tube, while the nephron forms from a cloud of mesenchymal cells that coalesce into epithelial vesicles. Each develops into a morphologically complex and highly differentiated structure, and together they provide essential filtration and resorption functions. In this review, we will consider their embryological origin and the genes controlling their morphogenesis, patterning, and differentiation, with a focus on recent advances in several areas.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 18, Issue 5, 18 May 2010, Pages 698–712
نویسندگان
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