کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2177692 1094668 2006 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Quantitative Modeling in Cell Biology: What Is It Good for?
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Quantitative Modeling in Cell Biology: What Is It Good for?
چکیده انگلیسی

Recently, there has been a surge in the number of pioneering studies combining experiments with quantitative modeling to explain both relatively simple modules of molecular machinery of the cell and to achieve system-level understanding of cellular networks. Here we discuss the utility and methods of modeling and review several current models of cell signaling, cytoskeletal self-organization, nuclear transport, and the cell cycle. We discuss successes of and barriers to modeling in cell biology and its future directions, and we argue, using the field of bacterial chemotaxis as an example, that the closer the complete systematic understanding of cell behavior is, the more important modeling becomes and the more experiment and theory merge.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 11, Issue 3, September 2006, Pages 279–287
نویسندگان
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