کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2178471 | 1549707 | 2012 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Human DHHC proteins: A spotlight on the hidden player of palmitoylation
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش گیاه شناسی
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Palmitoylation is one of the most common posttranslational lipid modifications of proteins and we now know quite a lot about it. However, the state of knowledge about the enzymes that catalyze this process is clearly insufficient. This review is focused on 23 human DHHC genes and their products - protein palmitoyltransferases. Here we describe mainly the structure and function of these proteins, but also, to a lesser degree, what the substrates of the enzymes are and whether they are related to various diseases. The main aim of this review was to catalogue existing information concerning the human DHHC family of genes/proteins, making them and their functions easier to understand.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Cell Biology - Volume 91, Issue 2, February 2012, Pages 107-117
Journal: European Journal of Cell Biology - Volume 91, Issue 2, February 2012, Pages 107-117
نویسندگان
Justyna Korycka, Agnieszka Åach, Elżbieta Heger, Dżamila M. BogusÅawska, Marcin Wolny, Monika Toporkiewicz, Katarzyna Augoff, Jan Korzeniewski, Aleksander F. Sikorski,