Two-component signal transduction in Agaricus bisporus: A comparative genomic analysis with other basidiomycetes through the web-based tool BASID2CS

► Agaricus bisporus contains eight genes coding for two-component system (TCS) proteins. ► Genomes of basidiomycetes show a conserved core complement of five TCS proteins. ► Dual-histidine kinases are limited to various species of basidiomycetes. ► The A. bisporus Skn7-like response regulator gene is up-regulated on compost. ► BASID2CS is a web server for large-scale TCS protein analyses of basidiomycetes.