کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2182523 1095467 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Expression of low density lipoprotein receptor-related protein 4 (Lrp4) gene in the mouse germ cells
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Expression of low density lipoprotein receptor-related protein 4 (Lrp4) gene in the mouse germ cells
چکیده انگلیسی

The low density lipoprotein receptor-related protein 4 gene (Lrp4) was identified by subtractive screening of cDNAs of the migratory primordial germ cells (PGCs) of E8.5–9.5 embryo and E3.5 blastocysts. Lrp4 is expressed in PGCs in the hindgut and the dorsal mesentery of E9.5 embryos, and in germ cells in the genital ridges of male and female E10.5–13.5 embryos. Lrp4 is also expressed in spermatogonia of the neonatal and adult testes and in the immature oocytes and follicular cells of the adult ovary. The absence of Lrp4 expression in the blastocyst, embryonic stem cells and embryonic germ cells suggests the Lrp4 is a molecular marker that distinguishes the germ cells from embryo-derived pluripotent stem cells.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene Expression Patterns - Volume 6, Issue 6, August 2006, Pages 607–612
نویسندگان
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