کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2183626 | 1550300 | 2008 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
From expression to signaling: Roles of TREM-1 and TREM-2 in innate immunity and bacterial infection
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیولوژی سلول
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: From expression to signaling: Roles of TREM-1 and TREM-2 in innate immunity and bacterial infection From expression to signaling: Roles of TREM-1 and TREM-2 in innate immunity and bacterial infection](/preview/png/2183626.png)
چکیده انگلیسی
Triggering receptor expressed on myeloid cells (TREM) proteins play important roles in innate and adaptive immunity. Since the discovery of TREM-1 and TREM-2 in 2000, the field has exploded over the past 8 years and currently TREM-1 is thought of as an amplifier of the immune response, while TREM-2 is believed to be a negative regulator. Here, we discuss the current state of the literature on TREMs, with a focus on TREM-1 and TREM-2 and their expression, signaling in mononuclear phagocytes and roles in innate immunity and bacterial infection.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunobiology - Volume 213, Issues 9–10, 6 November 2008, Pages 701–713
Journal: Immunobiology - Volume 213, Issues 9–10, 6 November 2008, Pages 701–713
نویسندگان
Omar Sharif, Sylvia Knapp,