Keywords: CARD، دامنه استخدام caspase; CARD, caspase recruitment domain; ASC, apoptosis-associated speck-like protein containing a CARD; NLR, nucleotide binding domain/leucine rich repeat; NLRP, NLR with pyrin domain; NLRC, NLR with CARD domain; MAPK, mitogen activated protein kinase; TRIF, TI
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Keywords: CARD، دامنه استخدام caspase; AIDS, acquired immunodeficiency syndrome; ASK1, apoptosis signal-regulating kinase 1; BCG, bacille Calmette–Guérin; CARD, caspase recruitment domain; FADD, Fas-associated protein with death domain; γδ, gamma-delta; HDT, host-directed therapy; HIV, human i
Keywords: CARD، دامنه استخدام caspase; AIM, absent-in-melanoma; CARD, caspase recruitment domain; CLR, C-type lectin receptor; DAMP, damage-associated molecular pattern; HMGB1, high-mobility group box 1 protein; HSC, heat shock cognate protein; HSP, heat shock protein; ICAM, intercellular adhe
Keywords: CARD، دامنه استخدام caspase; PD, Parkinson׳s disease; CARD, caspase recruitment domain; TUNEL, terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate-biotin nick end labeling; DLB, dementia with Lewy bodies; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP±,
Increased expression of NLRP3 inflammasome components and interleukin-18 in patients with bullous pemphigoid
Keywords: CARD، دامنه استخدام caspase; AIM2, absent in melanoma 2 protein; ASC, apoptosis-associated speck-like protein caspase recruitment domain; BP, Bullous pemphigoid; CARD, caspase recruitment domain; ELISA, enzyme-linked immunosorbent assay; HMGB1, high-mobility group-1; IFN, interferon;
Oligomerized CARD16 promotes caspase-1 assembly and IL-1β processing
Keywords: CARD، دامنه استخدام caspase; ANOVA, analysis of variance; ASC, apoptosis-associated speck-like protein containing a caspase recruitment domain; Bcl10, B-cell lymphoma/leukemia 10; BS3, bis(sulfosccinimidyl)suberate; CARD, caspase recruitment domain; CARMA1, CARD-membrane-associated g
Polymorphisms of nucleotide-binding oligomerization domain 2 (NOD2) gene in miniature dachshunds with inflammatory colorectal polyps
Keywords: CARD، دامنه استخدام caspase; AIC, Akaike information criteria; BIC, Bayesian information criteria; CARD, caspase recruitment domain; cDNA, complementary DNA; CI, confidence interval; IBD, inflammatory bowel disease; ICRP, inflammatory colorectal polyp; LOD, logarithm of odds; LRR, le
Early IFN type I response: Learning from microbial evasion strategies
Keywords: CARD، دامنه استخدام caspase; AIM2, absent in melanoma 2; APOBEC, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; ASC, apoptosis-associated speck-like protein containing a CARD; CARD, caspase recruitment domain; CDNs, cyclic dinucleotides; CLRs, C-type lectin recepto
Phosphorylation of Carma1, but not Bcl10, by Akt regulates TCR/CD28-mediated NF-κB induction and cytokine production
Keywords: CARD، دامنه استخدام caspase; TCR, T cell receptor; CARD, caspase recruitment domain; CBM, Carma1/Bcl10/MALT1Signal transduction; NF-κB; T cells; Phosphorylation; Akt
Autoimmune regulator is acetylated by transcription coactivator CBP/p300
Keywords: CARD، دامنه استخدام caspase; AIRE, autoimmune regulator protein; CBP, CREB-binding protein; APECED, autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy; CARD, caspase recruitment domain; SAND, Sp100, AIRE-1, NucP41/75, DEAF-1 domain; PHD, plant homeodomain; PML, promyelocy
Mitochondria and viruses
Keywords: CARD، دامنه استخدام caspase; ANT, adenine nucleotide translocator; CARD, caspase recruitment domain; HSV, herpes simplex virus; IFN, interferon; MAVS, mitochondrial antiviral signaling protein; MFN, mitofusin; MMP, mitochondrial membrane permeabilization; PTPC, permeability transitio
Sensing disease and danger: A survey of vertebrate PRRs and their origins
Keywords: CARD، دامنه استخدام caspase; NLR, NOD-like receptors; TLR, Toll-like receptors; PAMPS, pathogen associated molecular patterns; PRR, pathogen recognition receptors; CARD, caspase recruitment domain; ASC, apoptosis-associated speck-like protein; IL1b, interleukin 1 b; LRR, leucine-rich
CaMKII targets Bcl10 in T-cell receptor induced activation of NF-κB
Keywords: CARD، دامنه استخدام caspase; CaM, calmodulin; CaMK, CaM dependent kinase; TCR, T-cell receptor; PLC-γ, phospholipase C-γ; DAG, diacylglycerol; IP3, inositol 1,4,5-triphosphate; PKC, protein kinase C; CBM, Carma1, Bcl10, Malt1 complex; CARD, caspase recruitment domain; IKK, IκB kinase
Nlrp3: An immune sensor of cellular stress and infection
Keywords: CARD، دامنه استخدام caspase; ASC, apoptosis-associated speck-like protein containing a CARD; BIR, baculovirus IAP repeat; CAPS, Cryopyrin/Nlrp3-associated periodic syndromes; CARD, caspase recruitment domain; CLR, C-type lectin receptor; Ig, immunoglobulin; IL, interleukin; IL-1R1, I
Interaction of calmodulin with Bcl10 modulates NF-κB activation
Keywords: CARD، دامنه استخدام caspase; CaM, calmodulin; TCR, T cell receptor; BCR, B cell receptor; CBM, Carma1, Bcl10, Malt1 complex; IKK, IκB kinase; PKC, protein kinase C; CARD, caspase recruitment domain; IP3, inositol-1,4,5-triphosphate; CRAC, calcium release-activated Ca2+ channel; CaMK,
Highly diversified innate receptor systems and new forms of animal immunity
Keywords: CARD، دامنه استخدام caspase; CARD, caspase recruitment domain; Ig, immunoglobulin; LRR, leucine-rich repeat; mccTLR, multiple cysteine cluster TLR; NLR, NACHT domain leucine-rich repeat receptor; PAMP, pathogen associated molecular pattern; PRR, pattern recognition receptor; PYD, Pyr
Functional phenotypes and gene expression profiles of peripheral blood mononuclear cells in chronic hepatitis C patients who developed non-Hodgkin’s B-cell lymphoma
Keywords: CARD، دامنه استخدام caspase; AID, activation-induced cytidine deaminase; CARD, caspase recruitment domain; CHC, chronic hepatitis C; HCV, hepatitis C virus; B-NHL, B-cell non-Hodgkin’s lymphoma; NK, natural killer; PBMCs, peripheral blood mononuclear cellsHCV; Non-Hodgkin’s B-cell ly
Analysis of conservation in the Fas-associated death domain protein and the importance of conserved tryptophans in structure, stability and folding
Keywords: CARD، دامنه استخدام caspase; DD, Death domain; DED, Death effector domain; CARD, Caspase recruitment domain; PYD, Pyrin domain; Fadd-DD, Fas-associated death domain protein; WT, Wild-type; CD, Circular dichroismFas-associated death domain protein; Protein folding; Stability; Conserve
A negative regulator of delayed prostaglandin D2 production in mouse mast cells
Keywords: CARD، دامنه استخدام caspase; ASC, apoptosis-associated speck-like protein containing a caspase recruitment domain; BMMC, bone marrow-derived mast cell; CARD, caspase recruitment domain; CTMC, connective tissue mast cell; COX, cyclooxygenase; cPLA2α, cytosolic phospholipase A2 α; DNP,
From expression to signaling: Roles of TREM-1 and TREM-2 in innate immunity and bacterial infection
Keywords: CARD، دامنه استخدام caspase; Bacterial infection; Innate immunity; TREM-1; TREM-2AP-1, activator protein 1; Bcl-10, B cell lymphoma 10; BMDCs, bone marrow-derived dendritic cells; BMDM, bone marrow-derived macrophages; CARD, caspase recruitment domain; CD14, monocyte differentiation
p204, a p200 family protein, as a multifunctional regulator of cell proliferation and differentiation
Keywords: CARD، دامنه استخدام caspase; AIM2, absent in melanoma 2; ATM, ataxia telangiectasia mutated (protein kinase); ALP, alkaline phosphatase; BMP-2, bone morphogenetic protein-2; CARD, caspase recruitment domain; Cbfa1, core-binding factor l; CMV, cytomegalovirus; DAPIN, domain in apoptos
The interplay between viruses and innate immune signaling: Recent insights and therapeutic opportunities
Keywords: CARD، دامنه استخدام caspase; AdV, adenovirus; ASFV, African swine fever virus; CARD, caspase recruitment domain; CMV, cytomegalovirus; DC, dentritic cell; ds, double-stranded; EBV, Epstein-Barr virus; eIF, eukaryotic initiation factor; EMCV, encephalomyocarditis virus; FADD, Fas-asso
Erythropoietin: Elucidating new cellular targets that broaden therapeutic strategies
Keywords: CARD، دامنه استخدام caspase; Aβ, β-amyloid; AGES, advanced glycation endproducts; Akt, protein kinase B; Apaf-1, apoptotic protease-activating factor; ARNT, aryl hydrocarbon receptor nuclear translocator; CARD, caspase recruitment domain; DED, death effector domain; DM, diabetes mell
VISA—A pass to innate immunity
Keywords: CARD، دامنه استخدام caspase; CARD, caspase recruitment domain; dsRNA, double-stranded RNA; FADD, Fas-associated death domain protein; IRF3, interferon regulatory factor 3; IKK, IkappaB kinases; NF-κB, nuclear factor κB; RIG-I, RNA helicases protein retinoic acid-inducible gene I; RIP
Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes
Keywords: CARD، دامنه استخدام caspase; Asc, apoptosis associated speck-like protein containing a card; CARD, caspase recruitment domain; CNS, central nervous system; ELF, extremely low frequency; GSM, global system for mobile communication; MAPK, mitogen activated protein kinase; NF-κB, nuclea
Protease signalling in cell death: caspases versus cysteine cathepsins
Keywords: CARD، دامنه استخدام caspase; BH3, Bcl-2 homology region 3; Bid, BH3-interacting domain death agonist; CARD, caspase recruitment domain; DED, death effector domain; DISC, death-inducing signalling complex; IAP, inhibitor of apoptosis protein; TNF, tumor necrosis factorApoptosis; Caspa
Cytokine modulation of retinoic acid-inducible gene-I (RIG-I) expression in human epidermal keratinocytes
Keywords: CARD، دامنه استخدام caspase; CARD, caspase recruitment domain; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HCV, hepatitis C virus; IFN, interferon; IL, interleukin; IRF-3, interferon regulatory factor-3; MDA-5, melanoma differentiation-associated gene-5; RIG-I, retinoic acid-ind
Mitochondria and reactive oxygen species in renal cancer
Keywords: CARD، دامنه استخدام caspase; Mitochondria; Oxidative phosphorylation; Cancer; Reactive oxygen speciesAPAF-1, apoptotic protease activating factor-1; Bax, proapoptotic protein; Bcl-2, Bcl-xL, antiapoptotic proteins; CARD, caspase recruitment domain; CCRC, clear cell renal carcinoma; C
Splicing of NOD2 (CARD15) RNA transcripts
Keywords: CARD، دامنه استخدام caspase; Apaf-1, apoptotic protease activating factor 1; CARD, caspase recruitment domain; CATERPILLER, CARD, transcription enhancer, R (purine)-binding, pyrin, lots of leucine repeats; CD, Crohn's disease; EST, expressed sequence tag; GAPDH, glyceraldehyde-3-phos
Conserved function of caspase-8 in apoptosis during bony fish evolution
Keywords: CARD، دامنه استخدام caspase; ADAM19, a disintegrin and metalloproteinase domain 19; βGal, β-galactosidase; CARD, caspase recruitment domain; CASc, caspase catalytic domain; CHX, cycloheximide; CrmA, cytokine response modifier A; DD, death domain; DED, death effector domain; DISC, dea
Cytoplasmic Listeria monocytogenes stimulates IFN-β synthesis without requiring the adapter protein MAVS
Keywords: CARD، دامنه استخدام caspase; CARD, caspase recruitment domain; dsRNA, double-stranded RNA; ERK, extracellular signal-regulated kinase; IFN, interferon; IKK, IκB kinase; IRF3, interferon regulatory factor-3; MAVS, mitochondrial antiviral signaling; MDA5, melanoma differentiation-assoc
Apoptosis repressor with caspase recruitment domain (ARC) is expressed in cancer cells and localizes to nuclei
Keywords: CARD، دامنه استخدام caspase; ARC, apoptosis repressor with CARD domain; CARD, caspase recruitment domain; CK2, casein kinase II; Nop30, nucleolus protein of 30 kDa; NQO-1, NAD(P)H:quinone oxidoreductase 1; NLS, nuclear localization signal; YY-1, YinYang 1Apoptosis repressor with casp